منابع مشابه
Actin cytoskeleton: Thinking globally, actin’ locally
A class of proteins dubbed pipmodulins bind to and sequester the phospholipid PIP2 in the plasma membrane. Local release of PIP2 controls actin dynamics in specific subcellular regions and plays a critical role in regulating actin-based cell motility and morphogenesis.
متن کاملVisualising the actin cytoskeleton.
The actin cytoskeleton is a dynamic filamentous network whose formation and remodeling underlies the fundamental processes of cell motility and shape determination. To serve these roles, different compartments of the actin cytoskeleton engage in forming specific coupling sites between neighbouring cells and with the underlying matrix, which themselves serve signal transducing functions. In this...
متن کاملI-6: Role of Actin Cytoskeleton during Mouse Sperm Acrosomal Exocytosis
Background: Mammalian sperm must undergo a process termed capacitation to become competent to fertilize an egg. Capacitation renders the sperm competent by priming the cells to undergo a rapid exocytotic event called acrosomal exocytosis that is stimulated by the zona pellucida (ZP) of the egg or progesterone. Over the years, several biochemical events have been associated with the capacitation...
متن کاملThe Bacterial Actin Cytoskeleton
M icrobial shape, long used as a taxonomic criterion, is genetically determined. But how DNA sequence information is translated into morphology is a seminal question still without a complete answer for any microorganism. Recently, however, when investigators discovered that actin-like proteins are involved in determining bacterial cell shape, they revolutionized the field. This insight provides...
متن کاملTobacco WLIM1 is a novel F-actin binding protein involved in actin cytoskeleton remodeling.
We used confocal microscopy and in vitro analyses to show that Nicotiana tabacum WLIM1, a LIM domain protein related to animal Cys-rich proteins, is a novel actin binding protein in plants. Green fluorescent protein (GFP)-tagged WLIM1 protein accumulated in the nucleus and cytoplasm of tobacco BY2 cells. It associated predominantly with actin cytoskeleton, as demonstrated by colabeling and trea...
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ژورنال
عنوان ژورنال: Cell Structure and Function
سال: 2000
ISSN: 0386-7196,1347-3700
DOI: 10.1247/csf.25.291